Marcelo OliveiraMendoza isn’t a single wine route. Maipú, Luján de Cuyo, and Valle de Uco lie in different directions and at different distances, while the High Mountains take up a full day. In four days, the trip works best when each region gets its own dedicated time.
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Quick answer: Book four days: one for the city, two for wine regions, and one for the High Mountains. Use a driver, a tour, or hired transport on tasting days. Flexibility matters more than a rigid schedule.
How to plan your trip
Maipú is close and traditional; Luján de Cuyo combines well-known wineries with Chacras de Coria; Valle de Uco is farther out and offers vineyards with a stunning Andean backdrop. Many wineries require reservations, including for lunch. Choose no more than two or three per day.
Suggested itinerary
Day 1: city center, plazas, and Parque General San Martín. Day 2: Luján or Maipú. Day 3: Valle de Uco, if the budget and distance make sense. Day 4: Potrerillos, Uspallata, Puente del Inca, and Aconcagua viewpoints, depending on road and border conditions. Always leave a buffer for weather and delays.
Partner · Civitatissee all activities in Mendoza ›- See ›Mendoza New City Free TourRating 9.7 · 22 reviews on Civitatis
- See ›Mendoza Free Walking TourRating 9.1 · 716 reviews on Civitatis
- Andes High Mountain Day TripRating 8.8 · 1,044 reviews on Civitatisfrom€68.50per personSee ›
- Wine Tasting and Winery TourRating 8.9 · 992 reviews on Civitatisfrom€37.76per personSee ›
Civitatis prices on 28/09/2026, from, per person. They may change. Want to compare? Activities in Mendoza on GetYourGuide ›
When to go and what to know
March brings harvest season and events; spring favors green vineyards; winter shows snow-capped mountains but can affect the international route. Don’t confuse a High Mountain tour with a permit to climb Aconcagua.
Bookings, costs, and safety
Compare what’s included, read recent reviews, and save your reservations offline. Check Mendoza Turismo and the official wine tourism guide. Don’t skimp on safe transportation. Pair this trip with our Buenos Aires guide.
HotelAs soon as you have datesCompare neighbourhoods and guest ratings.Booking ›- ActivitiesBefore you travelBook ahead the ones with limited spots.Civitatis ›
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Frequently asked questions
How many days should I stay?
This itinerary covers four days: one for the city, two for wine regions and one for the High Andes. Each region gets its own day.
Do I need to book in advance?
Book visits and lunches at your chosen wineries. Plan Luján or Maipú on one day and Valle de Uco on another, checking transportation before booking.
Is it worth renting a car?
For tasting days, the itinerary recommends a driver, excursion or prearranged transportation. Consider a rental car for the other days separately, including the High Andes route.
What’s the most common mistake?
Treating Maipú, Luján and Valle de Uco as one region, or combining wineries with the High Andes. The itinerary separates these journeys by day.
Conclusion
Mendoza rewards those who respect distances, weather, and the local pace. Plan the essentials before the details.